Results 111 to 120 of about 14,394,948 (360)

By a Thread: The New Experience of America's Middle Class [PDF]

open access: yes, 2007
Developed in collaboration with the Institute on Assets and Social Policy at Brandeis University, By a Thread: The New Experience of America's Middle Class looks at the financial security of the middle class using the innovative Middle Class Security ...
Jennifer Wheary   +2 more
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Investigating the Influencing Factors on the Fashion Choices among the Girls Aged 15-20 in Shahrekord-Iran [PDF]

open access: yesفصلنامه زن و جامعه
Introduction: Discovering the various reasons for the young girls' tendency towards fashion choices, and giving direction to the way of choosing suitable clothing for society, is one of the concerns of the country today. This issue becomes more important
Elaheh Gholipour   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Use of granulands for analysis of social class [PDF]

open access: yes
In this paper, an analytical tool enabling the analysis of social stratification is proposed. The classical scheme for scaling consisting of two stages, conceptualisation and operationalization, is modified by the use of the concept of granulation ...
Luisa Canal,, Walenty Ostasiewicz
core  

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