Results 151 to 160 of about 3,377,764 (311)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Supermodular Social Games [PDF]

open access: yes
A social game is a generalization of a strategic-form game, in which not only the payoff of each player depends upon the strategies chosen by their opponents, but also their set of admissible strategies.
Ludovic Renou
core   +3 more sources

Rural class differentiation in Nigeria: Theory and practice - a quantitative approach in the case of Nupeland [PDF]

open access: yes
The knowledge of social stratification within the peasantry is a decisive precondition of sustainable economic and political measures for an effective support of agricultural production in least developed countries. This is one of the reasons why also in
Kohnert, Dirk
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Pursuing the American Dream: The Effect of Immigrant Settlement among Asian Americans and Occupational Disparities in Management

open access: yesSociation Today, 2013
It is well established that Asian Americans are fairly represented in professional occupations due to their high educational attainment. However, the representation of Asian Americans in managerial occupations is still small.
Hideki Morooka
doaj  

Class Origin, Family Culture, and Intergenerational Correlation of Education in Rural China [PDF]

open access: yes
This paper examines the determinants of intergenerational correlation of education in rural China by using a data from a large survey of households. Three generations who completed education during the period from pre-1949 to the beginning of the 2000s ...
Li, Shi, Sato, Hiroshi
core  

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

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