Results 161 to 170 of about 14,394,948 (360)
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Blood lipid associations in 18 year-old men
The association of cigarette smoking, physical activity at work, and social class with total cholesterol and with high and low density lipoprotein cholesterol were examined in a random sample of 238 males, of 18 years of age, of Rosario, Argerntina.
Leonor Poletto +2 more
doaj
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Race, social class, and parental involvement with children's cognitive development
Jeremy A. Pienik
openalex +2 more sources
Closing achievement gaps with a utility-value intervention: Disentangling race and social class.
J. Harackiewicz +4 more
semanticscholar +1 more source
Changing Social Class Identities in Post-War Britain: Perspectives from Mass-Observation [PDF]
The idea that class identities have waned in importance over recent decades is a staple feature of much contemporary social theory yet has not been systematically investigated using primary historical data.
Mike Savage
core
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
Social class differences in youths’ participation in organized sports: What are the mechanisms?
Patrick Lie Andersen, Anders Bakken
semanticscholar +1 more source
“New” and “Old” Social Risks: Life Cycle and Social Class Perspectives on Social Exclusion in Ireland* [PDF]
The life cycle concept has come to have considerable prominence in Irish social policy debate. However, this has occurred without any systematic effort to link its usage to the broader literature relating to the concept.
Bertrand Maitre, Christopher T. Whelan
core
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source

