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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Fearless: Maurice Phiri

open access: yes, 2013
As the class of 2017 joins Gettysburg College, we recognize first-year student, Maurice Wezi Phiri, who already has already showed his fearless commitment to social justice ...
Phiri, Maurice W.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Associação entre idade, classe social e hábito de fumar maternos com peso ao nascer

open access: yesRevista de Saúde Pública
Foi realizado inquérito em Ribeirão Preto, Brasil, de junho de 1978 a maio de 1979, que constou de entrevistas com mães de nascidos vivos hospitalares, de partos únicos, correspondendo a 98 % dos nascimentos ocorridos durante o período no Município.
Antonio A.M. da Silva   +5 more
doaj  

College integration and social class. [PDF]

open access: yesHigh Educ (Dordr), 2022
Álvarez-Rivadulla MJ   +5 more
europepmc   +1 more source

Inequality in individual mortality and economic conditions earlier in life [PDF]

open access: yes
We analyze the effect of being born in a recession on the mortality rate later in life in conjunction with social class. We use individual data records from Dutch registers of birth, marriage, and death certificates, covering the period 1815-2000, and we
Lindeboom, Maarten   +2 more
core  

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