Results 181 to 190 of about 3,377,764 (311)

The Role of Families in Shaping Youth Social Participation: Evidence from Singapore [PDF]

open access: yes
Youth participation in social groups is important in developing skills and experience for successful transition to adulthood. What kinds of families do youth who are active in social groups and who take on leadership positions come from?
Irene Y.H. Ng, K.C. Ho, Kong Weng Ho
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Factors affecting nutrition behavior among middle-class adolescents in urban area of Northern region of Brazil

open access: yesRevista de Saúde Pública
INTRODUCTION: Brazil has been called a nation in nutrition transitional because of recent increases in the prevalence of obesity and related chronic diseases.
Eva I. Doyle, Robert H. L. Feldman
doaj  

PERBANDINGAN MODAL SOSIAL ANGGOTA DI DUA KELOMPOK TANI (Studi Kasus Kelompok Tani Teratai Merah Dan Kelompok Tani Teratai Putih) [PDF]

open access: yes
Social capital has an important role in achieving the goals of farmer groups. Each member of a farmer group has different social capital, even though the farmer group is in the same area.
Hasan, Juhan Mahdum
core  

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

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