Results 201 to 210 of about 14,394,948 (360)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Factors affecting nutrition behavior among middle-class adolescents in urban area of Northern region of Brazil

Revista de Saúde Pública
INTRODUCTION: Brazil has been called a nation in nutrition transitional because of recent increases in the prevalence of obesity and related chronic diseases.
Eva I. Doyle, Robert H. L. Feldman
doaj  

What role does social class play in the impact of social environment on residents' health. [PDF]

Sci Rep
Liu Z, Su M, Zhang T, Zhang W, Li D.
europepmc   +1 more source

Second Birth Fertility in Germany: Social Class, Gender, and the Role of Economic Uncertainty. [PDF]

Eur J Popul, 2023
Kreyenfeld M, Konietzka D, Lambert P, Ramos VJ.   +3 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The paradoxical effects of social class on career adaptability: The role of intolerance of uncertainty. [PDF]

Front Psychol, 2022
Wang R, Lin X, Wang L.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Higher social class is associated with higher contextualized emotion recognition accuracy across cultures. [PDF]

PLoS One
Kafetsios K, Hess U, Alonso-Arbiol I, Schütz A, Gruda D, Campbell K, Chen BB, Dostal D, Held MJ, Hypsova P, Kamble S, Kimura T, Kirchner-Häusler A, Kyvelea M, Livi S, Mandal E, Ochnik D, Papageorgakopoulos N, Seitl M, Sakman E, Sumer N, Sulejmanov F, Theodorou A, Uskul AK.   +23 more
europepmc   +1 more source

中产阶层与社会发展 : 中国模式下的问题与挑战 = Middle class and social development : the problems and challenges in China

, 2015
平立 何
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source