Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Informed choices for some, but not for others: An exploration of Australian midlife women's participation in mammography screening by social class. [PDF]
Womens Health (Lond)Batchelor S +3 more
europepmc +1 more source
The influence of signs of social class on compassionate responses to people in need. [PDF]
Front Psychol, 2022 Callaghan B, Delgadillo QM, Kraus MW.
europepmc +1 more source
Social class and higher education : issues affecting decisions on participation by lower social class groups [PDF]
, 2001 Aston, Jane +5 more
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The dark side of the association between internet use and older adults' subjective wellbeing: the role of subjective social class. [PDF]
BMC GeriatrZhang D, Shi J, Feng Z.
europepmc +1 more source
A working class hero’s sidekick is something to be: sidekicks and underlings in British social realist cinema (1956-2014) [PDF]
, 2016 Anne-Lise Marin-Lamellet
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Social class group identity, intergroup attitudes, and views on social mobility and inequality in the U.K. and the U.S. [PDF]
Soc Issues Policy RevElenbaas L +9 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source