Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Religious beliefs and social class identification: micro evidence from China. [PDF]
Jiao J, Chen F, Gao S, Hu W.
europepmc +1 more source
The Effects of Subjective Social Class on Subjective Well-Being and Mental Health: A Moderated Mediation Model. [PDF]
Li K, Yu F, Zhang Y, Guo Y.
europepmc +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Bringing the group back in: Social class and resistance in adolescent smoking. [PDF]
McEvoy O, Layte R.
europepmc +1 more source
Shadow education, pandemic style: Social class, race, and supplemental education during Covid-19. [PDF]
Lee JC, Quadlin N, Ambriz D.
europepmc +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Informed choices for some, but not for others: An exploration of Australian midlife women's participation in mammography screening by social class. [PDF]
Batchelor S+3 more
europepmc +1 more source
Moderation modelling of COVID-19 digital health literacy and sense of coherence across subjective social class and age among university students in Ghana. [PDF]
Amoako I+5 more
europepmc +1 more source