Results 51 to 60 of about 14,394,948 (360)
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Social class and achievement case studies (National Strategies) [PDF]
, 2009 "This is the second part of a report of a National Strategies investigative project carried out in 2006–07 into the achievement of White British pupils from disadvantaged backgrounds.
core
On The Structure of Competitive Societies [PDF]
, 2005 We model the dynamics of social structure by a simple interacting particle system. The social standing of an individual agent is represented by an integer-valued fitness that changes via two offsetting processes.
Ben-Naim, E., Redner, S., Vazquez, F.
core +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
International Review of Social Psychology, 2017 Until recently, social class has been rarely studied in psychology, and when it was taken into account it was rather as a control demographic variable than as a variable of interest.
Sébastien Goudeau +2 more
doaj +1 more source
Community at the Courts: Social and Community Interactions at Public Basketball Courts [PDF]
, 2014 Based on over 60 informal interviews conducted at two public basketball courts, this study utilizes grounded theory to trace class- and race-based differences in the social interactions occurring at both parks.
Fogle, Elizabeth Arnaud
core +2 more sources
Rape and respectability: ideas about sexual violence and social class [PDF]
, 2009 Women on low incomes are disproportionately represented among sexual violence survivors, yet feminist research on this topic has paid very little attention to social class.
Alison Phipps +23 more
core +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Is a Growing Middle Class Good for the Poor? Social Policy in a Time of Globalization [PDF]
, 2017 We examine the effect of the rise and evolution of the middle class on extreme poverty, using the World Bank's international poverty line of $1.90 per person per day in 2011 purchasing power parity (PPP)- adjusted terms.
Homi Kharas, Raj M. Desai
core
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source