Results 51 to 60 of about 10,954,273 (361)

Determinants of Social-economic Mobility in the Northern Region of Malaysia [PDF]

open access: yesarXiv, 2020
Colleting the data through a survey in the Northern region of Malaysia; Kedah, Perlis, Penang and Perak, this study investigates intergenerational social mobility in Malaysia. We measure and analyzed the factors that influence social-economic mobility by using binary choice model (logit model). Social mobility can be measured in several ways, by income,
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The Relationship Between Social Class and Generalized Trust: The Mediating Role of Sense of Control

open access: yesFrontiers in Psychology, 2021
The success and well-being theory of trust holds that higher social class is associated with higher generalized trust, and this association has been well documented in empirical research.
Ruichao Qiang   +5 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A desigualdade invisível: o papel da classe social na criação dos filhos em famílias negras e brancas Invisible inequality: the role of social class in raising children from black and white families

open access: yesEducação em Revista, 2007
Apesar de a vida familiar ter um impacto importante nas oportunidades de vida dos filhos, os mecanismos pelos quais os pais transmitem essas vantagens ainda não são totalmente compreendidos.
Annette Lareau
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Social Algorithms [PDF]

open access: yes, 2018
This article concerns the review of a special class of swarm intelligence based algorithms for solving optimization problems and these algorithms can be referred to as social algorithms. Social algorithms use multiple agents and the social interactions to design rules for algorithms so as to mimic certain successful characteristics of the social ...
arxiv   +1 more source

The Interrelations Between Social Class, Personal Relative Deprivation, and Prosociality

open access: yesSocial Psychology and Personality Science, 2016
We propose that personal relative deprivation (PRD)—the belief that one is worse off than similar others—plays a key role in the link between social class and prosociality. Across multiple samples and measures (total N = 2,233), people higher in PRD were
Mitchell J. Callan   +3 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

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