Results 71 to 80 of about 8,328,870 (354)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The protective effect of neighbourhood social cohesion on adolescent mental health following stressful life events

Psychological Medicine, 2019
Background Exposure to stressful life events is an established risk factor for the development of adolescent mental disorder. Growing evidence also suggests that neighbourhood social environments, including strong social cohesion, could have a protective
M. Kingsbury, Zahra M. Clayborne, I. Colman, J. Kirkbride   +3 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Validating the dual evolutionary foundations of political values in a US sample

Frontiers in Psychology, 2023
Psychological research repeatedly identifies two dimensions of political values. Recent work argues that these dimensions reflect the dual evolutionary foundations of human social and political life: a trade-off between cooperation and competition that ...
Guy A. Lavender Forsyth, Ananish Chaudhuri, Quentin Douglas Atkinson, Quentin Douglas Atkinson   +3 more
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Citizen participation and its impact on political efficacy: insights from a town hall study in Germany

Frontiers in Political Science
This study investigates political efficacy—citizens’ beliefs in their ability to understand politics (internal political efficacy) and influence outcomes (external political efficacy)—in the context of town hall meeting (THMs) participation in a German ...
Yann P. M. Rees, Yann P. M. Rees, Leon Walter, Jonas Rees, Jonas Rees   +4 more
doaj   +1 more source

How to make social cohesion work. Bertelsmann Stiftung Speech 2019 [PDF]

, 2019
The megatrends of globalization and digitalization pose challenges for social cohesion. Many people are concerned about their economic future, and right-wing populists are leveraging the internet to spread oversimplified messages and fuel fears.
Saul, John Ralston
core  

Social cohesion revisited: a new definition and how to characterize it

Innovation: The European Journal of Social Science Research, 2018
This paper provides a general overview on different perspectives and studies on social cohesion, offers a definition of social cohesion that is deeply rooted in current literature, and provides a framework that can be used to characterize social cohesion
Xavier Fonseca, S. Lukosch, F. Brazier
semanticscholar   +1 more source

Team Incentives, Social Cohesion, and Performance: A Natural Field Experiment

Management Sciences, 2020
We conducted a field experiment in a Dutch retail chain of 122 stores to study the interaction between team incentives, team social cohesion, and team performance.
J. Delfgaauw, Robert Dur, O. Onemu, J. Sol   +3 more
semanticscholar   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source