Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Social comparison in the workplace: evidence from a field experiment [PDF]
We conducted a randomized field experiment to examine how workers respond to wage cuts, and whether their response depends on the wages paid to coworkers.
Alain Cohn +3 more
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La importancia de la magnitud de las protestas del movimiento Occupy: el caso de una protesta local como instrumento de comunicación mediante las Relaciones Públicas y los Medios Sociales [PDF]
, 2012 This paper explores the persuasive communications (public relations and branding through social media) of a micro Occupy event, namely a nine-day appearance of the global protest movement at Bournemouth University (BU), on the south coast of the UK. It
Adi, Ana, Moloney, Kevin
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Trust and Privacy Concern Within Social Networking Sites - A Comparison of Facebook and MySpace [PDF]
Trust and Privacy Concern Within Social Networking Sites - A Comparison of Facebook and MySpace - Analyzed ...
Sezavar Keshavarz, Amir
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Science led vs design led teaching approaches in materials science and engineering for aeronautical engineering students [PDF]
, 2013 A comparison on teaching styles has been conducted by analysing behavioural, cognitive, developmental, social cognitive and constructivist perspectives of 26 students (higher engineering apprentices).
Inam, Fawad
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Wohlfahrtseffek, Sozialreform, Vergleich, Vereinigte Staaten, Deutschland, Welfare effect, Social reform, Comparison, United states ...
Hans-Werner Sinn
core
Corporate Social Responsibility and the Non-commercial Sector [PDF]
, 2005 The paper offers a definition of the noncommercial sector (NCS) and outlines its properties in order to provide a comparison between the social responsibilities of businesses and the non-commercial sector. It suggests that assigning different levels
Seitanidi, M M
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