Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A New Social Conflict on Globalisation-Related Issues in Germany? A Longitudinal Perspective. [PDF]
Teney C, Rupieper LK.
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Social engagement revealed by gaze following in third-party observers of simulated social conflict. [PDF]
Champ TM +5 more
europepmc +1 more source
ORGANIC FARMING AND SOCIAL CAPITAL APPROACH IN THE RESTORATION OF SUSTAINABLE AGRICULTURAL LIVELIHOODS IN A POST-CONFLICT SETTING: A CASE OF NORTHERN UGANDA [PDF]
This report presents a discussion of how organic farming and social capital development can contribute towards the restoration of sustainable agricultural livelihoods in a post-conflict setting; with a case study of Northern Uganda.
Odokonyero, Kennedy
core
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Indigenous Theologies in Indonesia: Syncretism, State Recognition, and the Resilience of Aliran Kepercayaan [PDF]
This article provides a thorough examination of indigenous theology in Indonesia by focusing on the following six belief systems: Kejawen, Sunda Wiwitan, Kaharingan, Marapu, Ada’ Mappurondo, and Parmalim.
Cindy Vebyola Batubara +2 more
doaj +1 more source
Epidemics, pandemics, and social conflict: Lessons from the past and possible scenarios for COVID-19. [PDF]
Jedwab R, Khan AM, Russ J, Zaveri ED.
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Exploring motivated reasoning in polarization over the unfolding 2023 judicial reform in Israel
This work explored polarization over Israel’s Judicial Reform, introduced in January 2023. We find that the reform divided people into pro- and anti-reform camps, which differed in characteristics such as institutional trust, patriotism, and national ...
Dora Simunovic +2 more
doaj +1 more source

