Results 91 to 100 of about 859,029 (265)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Social engagement revealed by gaze following in third-party observers of simulated social conflict. [PDF]

open access: yesFront Psychol, 2022
Champ TM   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Exploring motivated reasoning in polarization over the unfolding 2023 judicial reform in Israel

open access: yesCommunications Psychology
This work explored polarization over Israel’s Judicial Reform, introduced in January 2023. We find that the reform divided people into pro- and anti-reform camps, which differed in characteristics such as institutional trust, patriotism, and national ...
Dora Simunovic   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Immigrant political participation is associated with more positive majority immigration attitudes across European countries and Swiss cantons

open access: yesComparative Migration Studies
Immigrants are increasingly participating in politics, publicizing their political concerns and contributions. How does such political participation relate to national majorities’ immigration attitudes?
Judit Kende   +4 more
doaj   +1 more source

Local knowledge matters: understanding the decision-making processes of communities under climate change in Suriname

open access: yesFrontiers in Climate
IntroductionTraditionally, local communities have relied on practical observations accumulated over extended periods to inform their decision-making.
Gwendolyn Smith   +2 more
doaj   +1 more source

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