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Racialized Representations of Migrants by the Local Police in Chile
In this article, we explore the racialized construction of migrants by the Carabineros, the Chilean national police. Based on a qualitative case study, we show that the representations of Latin American and Caribbean migrants by members of this ...
Cristián Doña-Reveco+2 more
doaj +1 more source
THE DOUKHOBORS IN CANADA - CONFLICT AND SOCIAL CHANGE, 1900-1976 [PDF]
Karen Bradley, James S. Frideres
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Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Research in Social Movements, Conflicts and Change: A Research Annual, Volume 4. Edited by Louis Kriesberg. Greenwich: JAI Press, 1981. 339 pp. $39.50 [PDF]
David M. Bush
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Employee Benefits and Social Welfare: Complement and Conflict [PDF]
Lawrence S. Root
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TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Social Philosophies in Conflict
V. J. McG, Joseph A. Leighton
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Economics of intolerance and social conflict
An important consensus today is that intolerance and social conflict have a substantial economic dimension. This article models a person's "returns" to acts of intolerance in terms of social approval or disapproval that this person's peer-group may offer.
openaire +3 more sources
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source