Results 91 to 100 of about 518,499 (284)

Is Large More Effective than Small is Beautiful? Size and Performance of Primary Schools in Poland [PDF]

open access: yes
We investigate the size-related features of the production function of Polish primary schools. The interplay of small schools ineffectiveness and of organizational and social difficulties appearing in large schools implies that the relationship between ...
Herbst, Mikolaj, Herczynski, Jan
core   +1 more source

Has Austerity Worked in Spain? [PDF]

open access: yes, 2015
Since 2011 Spain has pursued a set of economic policies for recovery based on internal currency devaluation, labor market reform, fiscal consolidation, and structural and deregulatory reforms such as the Market Unity Law, which are based on the idea of ...
David Rosnick, Mark Weisbrot
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Has EU Enlargement Been, and Will It Continue to Be, a Success? An Evaluation of EU Enlargement's Effects on Policies Pursued by Candidate Countries [PDF]

open access: yes
In this paper, I discuss whether enlargement has been a successful external policy of the European Union (EU). In particular, I evaluate the policy’s success based on its effects on the policies candidate countries have pursued. I argue that the prospect
Hlavac, Marek
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Agricultural Land Fragmentation and Land Consolidation Rationality [PDF]

open access: yes
Adopted about one year after the 1989 Revolution, Land Law (Law 18/1991) represented the starting point of land reform in Romania. As a result of this law implementation, at the beginning of the year 2000 the private sector owned 84% of total ...
Rusu, Marioara
core   +1 more source

Gender and democratic politics: a comparative analysis of consolidation in Argentina and Chile [PDF]

open access: yes, 2000
This article highlights a number of themes useful in the gendered analysis of democratic consolidation in Latin America by means of a comparative analysis of Argentina and Chile.
Waylen, G.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Identification of the Spatial Structure of Urban Polycentres Based on the Dual Perspective of Population Distribution and Population Mobility

open access: yesLand
The accelerated growth of urban areas has resulted in substantial alterations to the spatial structure of these settlements. The accurate identification of the multi-centre spatial structure is a fundamental prerequisite for the assessment of urban ...
Rongrong Zhang   +6 more
doaj   +1 more source

ANALYSIS OF THE BARRIERS LEADING TO FAILURE OF LAND CONSOLIDATION OF THE FIELDS [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2016
The biggest problem in transition from traditional agriculture to modern and up-to-date agriculture is the lack of land consolidation of the fields. The present study aimed to analyze the barriers to effective land consolidation of fields in the city of ...
Loghman RASHIDPOUR   +1 more
doaj  

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