Results 221 to 230 of about 11,902,515 (281)

black pr and social consolidation challenges

Актуальні проблеми філософії та соціології
openaire   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The social phenomenon of rare diseases: a logical-modal analysis. [PDF]

Front Sociol
Fernández-Vilas E, Coca JR, Plaza-Gómez N, Toscano FS.   +3 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Is There Still a Role for Autologous Stem Cell Transplantation in Older Adults with AML? [PDF]

Hematol Rep
Capria S, Minotti C, Breccia M, Bisegna ML, Carmosino I, Chiusolo P, Di Marino L, Luzi G, Mariani S, Marsili G, Marabitti L, Ortu La Barbera E, Scollo L, Martelli M, Trisolini SM.   +14 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Friendship segregation and class composition in schools: A systematic analysis of the role of attribute consolidation. [PDF]

PLoS One
Böller S, Kruse H.
europepmc   +1 more source

Opioid antagonist treatment in alcohol use disorder: extinction, reward memory, and the possible importance of timing. [PDF]

Front Neurosci
Jääskeläinen IP.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

[Rethinking Social accountability in Health]. [PDF]

Can Med Educ J
Saja F, Maherzi A.
europepmc   +1 more source