Results 51 to 60 of about 518,499 (284)

Catch Shares in Action: Peruvian Anchoveta Northern-Central Stock Individual Vessel Quota Program [PDF]

open access: yes, 2013
The Peruvian Anchoveta Northern-Central Stock Individual Vessel Quota Program is a catch share program that manages the largest volume fishery in the world.
Jeff Young, Kees Lankester
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Social Consolidation, Spatial Clustering, and Opinion Polarization

open access: yes, 2023
Network models of opinion formation highlight homophily and interpersonal influences as profound micro-mechanisms for opinion polarization. Yet, in these models, individuals are usually presumed to behave in a single dimension where opinions determine interactions and vice versa.
openaire   +1 more source

CONSOLIDATED BUDGET AS A SOCIAL DEVELOPMENT TOOL

open access: yesFinancial and credit activity problems of theory and practice, 2018
The financial system significant element is consolidated budget, which includes all levels budgets and certain types of centralized funds. The budget policy implemented through the system of budgetary mechanisms and should ensure budgetary equilibrium and effective impact on socio-economic processes.
Markuts, Y. I.   +2 more
openaire   +3 more sources

Efficiency as a determinant of loyalty among users of a community of clinical practice: a comparative study between the implementation and consolidation phases [PDF]

open access: yes, 2020
A community of clinical practice called the Online Communication Tool between Primary and Hospital Care (ECOPIH) was created to enable primary care and specialist care professionals to communicate with each other in order to resolve real clinical cases ...
Flayeh Beneyto, Souhel   +7 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Spatiotemporal characteristics and determinants of urban expansion in China: perspective of urban agglomerations

open access: yesFrontiers in Earth Science
IntroductionUrban agglomerations (UAs) are core economic growth centres, and urban construction land is the main spatial carrier of economic growth. Urban expansion is a research hotspot, while previous studies have rarely compared the characters and ...
Ming Li   +5 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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