Results 81 to 90 of about 14,435,174 (256)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mapping the e-business profile and trends in cost management in the UK construction industry [PDF]
, 2012 The advancement of e-business applications and IT infrastructure has had massive impact on construction business processes over the last decade. The added effects of globalisation coupled with global economic recession have forced businesses to implement
Zhou, Lei +5 more
core
Politikon, 2017 Extending on notions of securitisation and how it challenges democracy, this paper uses Marshall McLuhan’s tetrad of media effects within a social constructivist paradigm, to engage in an intertextual and intervisual analysis of political cartoons in ...
Dané Smith
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Analysis of the use of e-procurement in the public and private sectors of the UK construction industry [PDF]
, 2011 Summary: Eadie et.al (2010a, 2010b) identified 20 advantages in the adoption of e-procurement within a construction organisation. The Glover report (2008) indicated that by the end of 2010 all public sector procurement should be electronic.
Eadie, Robert +3 more
core
Environmentalism Without Nature? Steven Vogel’s post-natural environmental philosophy
Nordicum-Mediterraneum, 2020 Over the last 30 years quite a few writers have attacked the concept of nature as either ambiguous, meaningless, nostalgic or conservative (Foucault, Rorty, Latour, Descola etc.). Common for them have been their basis in some variant of constructivism or
Sune Frølund
doaj
IDENTITAS: KONSTRUKSI SOSIAL DAN KEKUASAAN
Islam Realitas: Journal of Islamic and Social Studies, 2018 This paper examines the construction of social identity that occurred in the Chinese society of Indonesian descent. Discrimination and violence against ethnic Chinese are common.
Endrizal Endrizal +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The state of the art in e-business: A case study from the Chinese construction industry [PDF]
, 2012 In the 21st century, e-business is seen as the new frontier. Currently e-business has been widely used in other industry and to some extent in global construction market, particularly in developed countries, such as UK, EU and USA.
Zhou, Lei +4 more
core