Results 81 to 90 of about 309,699 (265)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Valeurs et normes sociales dans le projet d'émancipation de Cornelius Castoriadis

Labyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics, 2019
The purpose of this article is to analyze the philosophy of values developed by Cornelius Castoriadis from his theory of the imaginary institution of societies. By understanding the emergence of imaginary significations, it is possible to identify their
Christophe Premat
doaj  

Creating social value within and between organisations

, 2022
This chapter discusses different ways of creating social value. We first present ideas about strategic, organisation level thinking. We highlight a partnership model which construction firms may find useful in co-creating social value in collaboration ...
Gorse, C, Raiden, A, King, A, Loosemore, M   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

What construction topics do they discuss in social media? : a case study of Weibo in China

, 2018
As a traditional industry such as the construction, it is hard to collect data for management and improvement. Traditional ways such as questionnaire survey, interviews, or focus meetings to collect data are both time- and cost-consuming.
Yoon, Yoojung, Song, Yangqiu, Tang, Liyaning (R19584), Zhang, Yiming, Dai, Fei   +4 more
core  

Impact of social safety investments on social costs of construction accidents

, 2004
Most contractors' financial losses associated with accidents, but not all, are also social costs. Some social costs are not incurred by contractors, but by society. Social costs of construction accidents have been gathered for years 1999-2001. The safety
Y. L. Chan, K. C. Ying, Chan, YL, W. Y. Chan, Tang, SL, Chan, WY, S. L. Tang, Ying, KC   +7 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Analysis of the use of e-procurement in the public and private sectors of the UK construction industry

, 2011
Summary: Eadie et.al (2010a, 2010b) identified 20 advantages in the adoption of e-procurement within a construction organisation. The Glover report (2008) indicated that by the end of 2010 all public sector procurement should be electronic.
Eadie, Robert, Perera, Srinath (R18622), Perera, Srinath, Heaney, George   +3 more
core  

Quality and safety in the palestinian construction industry [PDF]

, 2009
Construction industry is one of the largest and most important industries in Palestine. Quality and safety in the industry still suffers from ignorance and lack of supervision and accident rate on construction projects is very high. The objective of this
Choudhry, Rafiq M., Choudhry, R, Abu Alqumboz, Moheeb, Abualqumboz, M, Enshassi, Adnan, Choudhry, Rafiq M, Choudhry, Rafiq, Abualqumboz, Moheeb, Enshassi, A   +8 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source