Results 251 to 260 of about 13,951,403 (309)

Retraction Analysis in Social Media Research: A Scopus Based Data From 2011 to 2025. [PDF]

J Korean Med Sci
Kocyigit BF, Mukhamediyarov M, Qumar AB, Fedorchenko Y, Zimba O.   +4 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Dietary Patterns and the Social Development Index in Mexico City: A Machine-Learning Approach. [PDF]

Nutrients
Martínez-García M, Gutiérrez-Esparza G, Salazar MDCG, Amezcua-Guerra LM, Hernández-Lemus E.   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

From Tool to Social Actor: A Systematic Review of the Psychological Mechanisms Through Which Conversational AI Reshapes the Employee Experience. [PDF]

Behav Sci (Basel)
Liu L, Zhang R, Su X.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Sharing for the common good: Children's levels of social inclusion within the group and their sharing decisions in a public goods game. [PDF]

Br J Soc Psychol
Malin Y, Sabato H.
europepmc   +1 more source

Memoria de actividades del Consejo Económico y Social de Aragón.: 2011 [PDF]

, 2011
Consejo Económico y Social de Aragón., Consejo Económico y Social de Aragón   +1 more
core  

Patient and Public Involvement and Engagement (PPIE) in methodological research: exploring challenges, tensions and learning from the perspectives of PPIE and researchers in the Realist Economic Evaluation Methods (REEM) study. [PDF]

Res Involv Engagem
Fletcher A, Rook V, Mountain S, Shenton F, Fenocchi L, Kumar MB, Dalkin S, Bate A, Hunter R.   +8 more
europepmc   +1 more source