Results 191 to 200 of about 1,415,295 (314)
Relation between neighborhood socio-economic characteristics and social cohesion, social control, and collective efficacy: Findings from the Boston Neighborhood Study. [PDF]
Pabayo R +4 more
europepmc +1 more source
Simulated social control for secure Internet commerce [PDF]
Lars Rasmusson, Sverker Jansson
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Oral rehydration and social change: the control of diarrheal diseases in the Third World.
Alfred Yankauer
openalex +2 more sources
In vivo analysis of germ cell apoptosis reveals the existence of stage‐specific `social' control of germ cell death in the seminiferous epithelium [PDF]
Josefa Blanco‐Rodríguez +1 more
openalex +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Sociale controle en totale controle
Big data analyses worden steevast verdedigd met anekdotische succesverhalen waarbij het om gericht oogsten van vooraf geselecteerde gegevens gaat, een instrument voor statistisch onderzoek. Op internet vinden we evenwel een andere inzet van big data analyses, die gebaseerd zijn op een drang om al wat gedigitaliseerd kan worden op arbitraire wijze te ...
openaire +2 more sources
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source

