Results 31 to 40 of about 7,469,552 (341)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Arts and Crafts School of Medellín and artisan professionalization. 1869-1901

open access: yesHistoria y Sociedad, 2014
Historians have long recognized Colombia¿s artisans of the second half of the nineteenth century as a dynamic group who played an active role in the country¿s political movements.
Juliana Álvarez Olivares
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Social Media under Social Control: Regulating Social Media and the Future of Socialization [PDF]

open access: yes, 2010
The process of socialization for new and future journalists will look dramatically different from the process undergone by previous generations of journalists, due to economic realities and changes in the nature of news production.
Sivek, Susan Currie
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Corporate totalitarianism: an analysis of Bata system in Brazil and Chile (1940-1970)

open access: yesRevista Mundos do Trabalho, 2020
During the 1930s, the Czech company Bata Shoes Corporation became a well-established multinational organization. It figured amidst the largest shoes producers in the world, being a pioneer in carrying out economic, organizational and social ...
Vinícius de Rezende
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

ACCESS CONTROL IN A SOCIAL NETWORKING ENVIRONMENT [PDF]

open access: yes, 2013
Collecting users into groups is a common activity in social networking sites such as Facebook, Google groups, Yahoo groups and many other web applications. This project explores access control techniques for dynamically created groups. The starting point
Perepa, Mallika
core   +1 more source

(Breaking) the Law: Social Control, Self-Help and Violence in the Tale of Gamelyn

open access: yesStudia Anglica Posnaniensia, 2013
Fourteenth century England experienced social changes which influenced the attitude to crown law and triggered a growing distrust to law and its representatives.
Ludwikowska Joanna
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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