Results 51 to 60 of about 1,415,295 (314)

La Sección Femenina de Falange como guía adoctrinadora de la mujer durante el Franquismo / The female section of the fascist-inclined Phalange like an indoctrination guide of women during Francoism

open access: yesAsparkía, 2017
RESUMEN: Este estudio se ha titulado La Sección Femenina de Falange como guía adoctrinadora de la mujer durante el Franquismo, puesto que pretende abordar la situación de la mujer desde un punto de vista social, cultural, político y económico durante un ...
Desire Rodríguez Martínez
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Humans as Data

open access: yesPress Start, 2021
The fear of humans abusing technology to control others and the sociopolitical order has been at the heart of many dystopian stories. This fear is also at the heart of Watch_Dogs 2, where the centralized city-wide management system made by the Blume ...
Kai Kehrer
doaj  

Controle social nas organizações [PDF]

open access: yesRevista de Administração de Empresas, 1979
O presente trabalho apresenta vários aspectos do controle social nas organizações e analisa as contribuições de Merton, Selznick, Goudner, Crozier, o grupo de Aston e Weber. Foi originariamente publicado por Motta em 1979, e é revisitado por Vasconcelos e Wood Jr., que atualizam a bibliografia e adicionam alguns comentários, acrescentando a perspectiva
openaire   +9 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

« Il te faut mener une vie régulière » : prescriptions et rôle du père durant la grossesse (1960-1962)

open access: yesGenre, Sexualité et Société, 2017
Drawing on a micro-historical study of the correspondence between a couple of primary school teachers in the beginning of the 1960s, this article analyzes the role of fathers during pregnancy.
Fabien Deshayes, Axel Pohn-Weidinger
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Trayectorias contemporáneas del miedo en América Latina

open access: yesLes Cahiers ALHIM, 2017
At the beggining of XXI century, collective fears have dramatically transformed in Latin America. Although this modification is general, it carries specific expressions in each context and Latin America combines a remarkable mixture between changes in ...
David  Barrios Rodríguez
doaj   +1 more source

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