This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
The internal democracy of the crisis parties in Western Europe: a quantitative analysis of the role of digitalization, ideology and populism. [PDF]
Bronet J, Borge R.
europepmc +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Analyzing Misinformation and Disinformation: Understanding Swiss COVID-19 Narratives Through Natural Language Processing Analysis. [PDF]
Germani F +4 more
europepmc +1 more source
A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra +8 more
wiley +1 more source
Awareness of HPV and HPV vaccine among women with high-risk HPV types in the Mediterranean region. [PDF]
İşcan SC +3 more
europepmc +1 more source
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Democratic Deterrence of Middle Powers in Great Power Rivalry: The Case for Indonesia. [PDF]
Purboadji A.
europepmc +1 more source
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang +13 more
wiley +1 more source
Citizen participation in climate politics. Drivers and barriers of Climate Assemblies in Europe. [PDF]
Griessler E +6 more
europepmc +1 more source

