Results 41 to 50 of about 409,797 (306)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Infill Development and Its Impact on Various Components in Zanjan deteriorated areas [PDF]
نشریه جغرافیا و برنامهریزی, 2020 Introduction ach form of urban development has its own characteristics and disadvantages or advantages. But the common denominator of all these development patterns has been responding to the growing development of cities and preventing irregular growth.
ahmad asadi, Mohammad Reza Pourmohammadi
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Moral exclusion in the context of social desirability
RUDN journal of Sociology, 2022 The article considers such terms as social and moral exclusion in the context of the empirical study of collective representations. The authors define the origins of both terms and name those social groups that have historically been subject to exclusion
Zh. V. Puzanova, A. G. Tertyshnikova
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Acta Médica Portuguesa, 2005 Self-report of dietary intake could be biased by social thus affecting risk estimates in epidemiological studies. The objective of study was to assess the effect of social desirability on dietary intake from a food frequency questionnaire (FFQ).A ...
Renata Barros +2 more
doaj +1 more source
Desirability and social ranking
Social Choice and WelfareAbstract We present an axiomatic study of various solutions to the social ranking problem, where a solution links any ranking of coalitions of players to a binary relation between individual players. We focus on solutions that align with the desirability relation, asserting that player i
Aleandri, Michele +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Evaluation of the Relationship between the Dimensions of the Nurses’ Quality of Working Life and Social Desirability in Fars Province, Iran [PDF]
Journal of Kerman University of Medical Sciences, 2016 Background & Aimes: The nurses’ quality of working life (QWL) influences the quality of health services provided by them and can be affected by several factors. In this study, we assessed the effect of social desirability on nurses’ QWL in Fars province,
Narges Roustaei +4 more
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