Results 131 to 140 of about 13,068,156 (268)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A Conceptual Framework for Action on the Social Determinants of Health
Conceptual frameworks in a public health context shall in the best of worlds serve two equally important purposes: guide empirical work to enhance our understanding of determinants and mechanisms and guide policy-making to illuminate entry points for ...
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Triad of determinants of the safety of social workers: Personal determinants [PDF]
Social workers' safety is being conditioned with appropriate determinants. The basic determinants include system determinants, personal determinants and environmental determinants.
Arkadiusz, Żukiewicz,
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Background For over a decade, the maternal health discourse has focused on a phenomenon that is alternatively termed “obstetric violence,” “disrespect and abuse” (D&A) or the “mistreatment of women” in institutional obstetric care.
V. Srinidhi +8 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Health and its Social Determinants
Objectives: To analyze the relationship between health and social determinants, as well as presenting the objectives and lines of action of the National Commission on the Social Determinants of Health (NCSDH) created in Brazil in ...
Buss, P, Pellegrini Filho, A
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Background and Objective: Leadership style or behavior is an effective factor in employee performance. The purpose of the study was to determine heads' leadership style and its relationship with job satisfaction and burnout in staff of Shomal health ...
Mohammad-Hossein Safi +3 more
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Social capital and self-rated health in the Republic of Ireland: evidence from the European Social survey [PDF]
This paper analyses the determinants of self-reported health in Ireland, conditioning self-reported health on a set of socio-economic, labour market and social capital variables.
Wall, Patrick +4 more
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