Results 221 to 230 of about 1,151,198 (342)

Social Determinants of Health

ACSM'S Health & Fitness Journal, 2010
Nico Pronk, Thomas Kottke
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Social Determinants of Health and Clinical Outcomes in Hypertrophic Cardiomyopathy.

JAMA Cardiol
Hafeez N, Claggett BL, Owens AT, Helms AS, Saberi S, Lampert R, Stendahl JC, Ashley EA, Parikh VN, Lakdawala NK, Ingles J, Olivotto I, Ho CY, Taylor MR, Khan SS, Day SM.   +15 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Social determinants of health equity for people with pain: from understanding to action. [PDF]

Pain Rep
Walker E, Karran EL, Jones MD, Gibbs MT, Sharma S.   +4 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Impact of Social Determinants of Health in the Treatment of Closed Nasal Bone Fractures. [PDF]

Craniomaxillofac Trauma Reconstr
Frisco NA, Clark NW, Kilpatrick KW, Kuchibhatla M, Powers DB, Woodard CR, Osazuwa-Peters N, Barrett DM.   +7 more
europepmc   +1 more source

Addressing social determinants of mental health: a new era for prevention interventions [PDF]

Crick Lund
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Association Between Neighborhood Social Determinants of Health and Stillbirth. [PDF]

Obstet Gynecol
Kawakita T, Hayasaka M, Harper AM, Brush J, Saade G.   +4 more
europepmc   +1 more source