Results 121 to 130 of about 18,706 (300)

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Replication Data for: A Discounting Rule for the Social Cost of Carbon

open access: yes
Replication code for "A Discounting Rule for the Social Cost of Carbon" by Richard Newell, William Pizer, and Brian Prest, accepted at JAERE. The code calibrates discounting parameters (rho and eta) in a Ramsey-like discounting rule for estimating the ...
Prest, Brian   +2 more
core   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

fMRI - Social Delay Discounting Task (SDDT)

open access: yes
The fMRI - Social Delay Discounting Task measures brain activity during the Social Delay Discounting Task that measures impulse control in a social context.
Leiden Consortium on Individual Development
core   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova   +5 more
wiley   +1 more source

Mental health and socio-cognitive predictors of adherence to COVID-19 social distancing rules in adolescents in England

open access: yesHeliyon
The COVID-19 pandemic prompted governments worldwide to introduce social distancing measures, including school closures and restrictions on in-person socialising. However, adherence to social distancing was challenging for many – particularly adolescents,
Giacomo Bignardi   +10 more
doaj   +1 more source

Ethical Aspects of Intertemporal Discounting and the Social Discount Rate

open access: yesHitelintézeti szemle, 2018
The paper examines the ethical aspects of discounting during the preparation of intertemporal decisions, and the influence of this on the cost-benefit analysis of community investments. It focuses on the economic philosophy and ethical considerations that underlie discounting as a daily financial activity.
openaire   +2 more sources

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić   +4 more
wiley   +1 more source

Little evidence that androstadienone affects social distance-dependent prosocial behaviour: a pre-registered study

open access: yesRoyal Society Open Science
In navigating the complexities of social life, humans have evolved to interpret invisible odorous chemical cues, with profound behavioural impacts often unbeknown to the conscious mind.
Junsong Lu, Yuting Ye, Yin Wu
doaj   +1 more source

Deriving time discounting correction factors for TTO tariffs

open access: yes
The Time Tradeoff (TTO) method is a popular method for valuing health state utilities and is frequently used in economic evaluations. However, this method produces utilities that are distorted by several biases.
Attema, Arthur, Brouwer, Werner
core  

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