Results 51 to 60 of about 13,614,628 (308)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Multiple discrimination in law [PDF]

open access: yes, 2011
The paper forms part of the project 'GenderRace - The Use of Racial Anti-Discrimination Laws: Gender and Citizenship in a Multicultural Context', funded by the EU Seventh Framework Programme, Grant Agreement - SSH7-CT-2007-217237Acknowledgement: The ...
Howard, Erica   +2 more
core  

Inquisition and Purity of Blood in Portugal during the Seventeenth Century

open access: yesReligions, 2023
The aim of this paper is to analyse the role played by the Portuguese Holy Office in the process of social discrimination against New Christians, that is, those who were considered to be descendant of Jews converted to Christianity in the late fifteenth ...
Ana Isabel López-Salazar Codes
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Analysing the experience of discrimination in Ireland [PDF]

open access: yes, 2012
Discrimination undermines equality, and may have damaging consequences for the particular individuals involved. Monitoring the extent of discrimination is thus a very valuable exercise.
Watson, Dorothy   +2 more
core   +1 more source

Methodological issues in predicting discrimination from attitudes, prejudices, and stereotypes

open access: yes, 2015
A central question for social psychologists is to what extent attitudes, prejudice, and stereotypes are precursors of ethnic and racial discrimination.
Carlsson, Rickard, Agerström, Jens
core   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Social Behavior as Discriminative Stimulus and Consequence in Social Anthropology [PDF]

open access: yesThe Behavior Analyst, 1992
A behavior analysis is provided for three topics in social anthropology. Food, social relations, and ritual behaviors can enter into contingencies both as functional consequences and as discriminative stimuli for the reinforcement of behaviors through generalized social consequences.
openaire   +2 more sources

A Political Economy of Social Discrimination [PDF]

open access: yesJournal of the European Economic Association, 2019
<div> <div> This paper studies the causes and consequences of social discrimination. We consider a labor market in which payoff-irrelevant identity traits can shape hiring decisions. Identity is malleable and a majority group member can become socially associated with the minority group.
Torun Dewan, Stephane Wolton
openaire   +1 more source

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