Results 101 to 110 of about 11,805,971 (284)

Determinants of social distancing.

, 2022
Determinants of social distancing.
Sacha Dray (12568586), Timothy Besley (12568583)   +1 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COVID-19 and social distancing measures in Queensland, Australia, are associated with short-term decreases in recorded violent crime

, 2020
Objectives: The objective of this study is to test whether recorded rates of violent crime declined in the context of social distancing regulations in Queensland, Australia. Methods: ARIMA modeling was used to compute 6-month-ahead forecasts of rates for
Morgan, A, Payne, JL, Piquero, AR
core   +1 more source

Distancing and limited resourcefulness: Third sector service provision under austerity localism in the north east of England [PDF]

, 2015
Drawing on the concept of ‘austerity localism’, (Featherstone et al., 2012) this paper explores the impact of recent spending cuts and a revitalisation of the localism agenda on the work of locally embedded third sector organisations who work with ...
Donovan, Catherine, Merchant, Jacqueline, Clayton, John, Merchant, Jacqui   +3 more
core   +1 more source

Measures of social distancing, strictness of social distancing rules and other variables, by state, Brazil.

, 2022
Measures of social distancing, strictness of social distancing rules and other variables, by state, Brazil.
Rodrigo Fracalossi de Moraes (12256802), Louise B. Russell (9670101), Lara Livia Santos da Silva (5787422), Cristiana M. Toscano (12256805)   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Coronavirus risk perception and compliance with social distancing measures in a sample of young adults: Evidence from Switzerland

, 2021
The health risk of the coronavirus pandemic is age-specific. The symptoms of a COVID-19 infection are usually mild in the healthy population below the age of 65; however, the measures laid down to prevent the spread of the virus apply typically to the ...
Franzen, Axel, Wöhner, Fabienne
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Increased meaningful activity while social distancing dampens affectivity; mere busyness heightens it: Implications for well-being during COVID-19.

PLoS ONE, 2020
Social distancing measures have been implemented in many countries to limit the spread of COVID-19. Emerging literature reveals that fear of acquiring COVID-19 has detrimental psychological ramifications.
Daniel B Cohen, Morgan Luck, Atousa Hormozaki, Lauren L Saling   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source