Results 81 to 90 of about 403,673 (309)

Editorial: Distributed and embodied cognition in scientific contexts

Frontiers in Psychology, 2023
Majid D. Beni, Ahti-Veikko Pietarinen, Mirko Farina   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Brain development in a facultatively social allodapine bee aligns with caste, but not group living

Frontiers in Ecology and Evolution
IntroductionThe ‘social brain hypothesis’ proposes that brain development (particularly primates) is driven by social complexity, more than group size. Yet, small insects with minute brains are capable of the most complex social organization in animals -
Simon M. Tierney, Sarah Jaumann, Oliver Hightower, Adam R. Smith   +3 more
doaj   +1 more source

Innovative Methods of Teaching Science and Engineering in Secondary Schools [PDF]

Journal of Systemics, Cybernetics and Informatics, 2006
This article describes the design of an interactive learning environment to increase student achievement in middle schools by addressing students' preconceptions, and promoting purposeful social collaboration, distributed cognition, and contextual ...
Nathan BALASUBRAMANIAN, Brent G. WILSON, Krzysztof J. CIOS   +2 more
doaj  

Profiles of Emotion Regulation: Understanding Regulatory Patterns and The Implications for Posttraumatic Stress [PDF]

, 2017
Trauma survivors often experience posttraumatic stress (PTS) and report concurrent difficulties with emotion regulation (ER). Although individuals typically use multiple regulatory strategies to manage emotion, no studies yet examine the influence of a ...
Chesney, Samantha, Gordon, Nakia
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

A framework for developing and implementing an online learning community [PDF]

, 2011
Developing online learning communities is a promising pedagogical approach in online learning contexts for adult tertiary learners, but it is no easy task.
Cowie, Bronwen, Khoo, Elaine G.L.
core   +2 more sources

When decision support systems fail: insights for strategic information systems from Formula [PDF]

, 2018
Decision support systems (DSS) are sophisticated tools that increasingly take advantage of big data and are used to design and implement individual - and organization - level strategic decisions .
Arnott, Aversa, Aversa, Baesens, Barney, Bernhard, Boland, Brynjolfsson, Cabantous, Cabantous, Callon, Callon, Callon, Castellucci, Cecez-Kecmanovic, Cecez-Kecmanovic, Chen, Chen, Constantiou, Corley, Davenport, Dean, DeSanctis, DeSanctis, Earl, Elbanna, Erden, Feldman, Forbes, Fredrickson, Galliers, Garud, George, Gherardi, Gibson, Gino, Gioia, Gioia, Giraudeau, Gregor, Günther, Hedberg, Hevner, Hevner, Hutchby, Hutchins, Hutchins, Jacobs, Jarzabkowski, Jenkins, Junglas, Kahneman, Laure Cabantous, LaValle, Lazer, Leonardi, Loebbecke, MacKenzie, MacKenzie, MacKenzie, Manktelow, March, March, Marino, Markus, Mayer-Schönberger, Mazmanian, McAfee, McDermott, Morgan, Nicolini, Nicolini, Orlikowski, Orlikowski, Orlikowski, Paolo Aversa, Peppard, Scarbrough, Schein, Siggelkow, Stefan Haefliger, Strauss, Suppiah, Vaara, Vallee-Tourangeau, Van Maanen, Villejoubert, von Krogh, Wagner, Weick, Whittington, Zammuto, Zigurs   +92 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source