Results 51 to 60 of about 802,990 (301)

How do Saudi EFL learners realize the speech act of request?

open access: yesCogent Arts & Humanities, 2023
The current study aimed to examine the realization of the speech act of request by Saudi EFL learners, in Arabic as their first language and English as their foreign language.
Dina Abdel Salam El-Dakhs   +2 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

The Influence of Unlimited Sucrose Intake on Body Weight and Behavior—Findings from a Mouse Model

open access: yesBrain Sciences, 2022
A potential relationship between unrestricted sucrose intake (USI), overweight, and emotional/behavioral control has not been well documented. We examined the influence of USI and having less sweetness than expected on body weight (BW), motor/exploratory,
Olga Dubljević   +4 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

The Pathway between Social Dominance Orientation and Drop out from Hierarchy-Attenuating Contexts: The Role of Moral Foundations and Person-Environment Misfit

open access: yesBehavioral Sciences, 2023
The present study examines the role of individuals’ preference for unequal intergroup relations in exacerbating a process of differential attrition from organizations that value intergroup equality (i.e., hierarchy-attenuating contexts). We proposed that
Alessio Tesi   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Oppositional Decoding Influences under Stuart Hall: A Case Study of the Advertisement “The NFL is for everyone”

open access: yesExpose, 2023
Social Justice Content Marketing (SJCM) presents unique challenges to the marketer beyond the traditional marketing tools used to message the consumer effectively.
Daniel Blanchett   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Policing in nonhuman primates: partial interventions serve a prosocial conflict management function in rhesus macaques. [PDF]

open access: yes, 2013
Studies of prosocial policing in nonhuman societies traditionally focus on impartial interventions because of an underlying assumption that partial support implies a direct benefit to the intervener, thereby negating the potential for being prosocial in ...
Beisner, Brianne A, McCowan, Brenda
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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