Results 41 to 50 of about 14,661 (275)

Survival of the fittest in the pandemic age: Introducing disease-related social Darwinism

open access: yesPLoS ONE, 2023
COVID-19 was a harsh reminder that diseases are an aspect of human existence and mortality. It was also a live experiment in the formation and alteration of disease-related attitudes.
Paul Nachtwey, Eva Walther
doaj   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Social justice representations and social dominance orientation in primary teacher training students

open access: yesINFAD, 2019
Recently, research have focused on analyzing the Social Justice representations in the educational field. Based on the tridimensional Social Justice issues, described by Nancy Fraser, this research focus on three dimensions: Redistribution, Recognition ...
Miguel Ángel Albalá Genol   +1 more
doaj   +1 more source

Orientation to social dominance: a psychological invariant in the legitimation of social inequality philosophies

open access: yesRevista Científica Arbitrada de la Fundación MenteClara, 2020
Different theoretical approaches throughout history have tried to explain why societies establish ideologies that think intergroup relationships as unequal and hierarchical, and why it is accepted by individuals.
Luis Carlos Jaume   +2 more
doaj   +1 more source

Are we Europeans?: Correlates and the relation between national and European identity [PDF]

open access: yesPsihologija, 2009
Researches of the correlates of the national identity are plentiful both in Serbian and foreign literature. However, in the past decade or so, a new social identity starts to make its way into the researches of the social psychologists-European identity ...
Mihić Vladimir
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Weighing the Options

open access: yesJournal of Intercollegiate Sport, 2016
In drawing from multiple theoretical frameworks, including stigma theory (Goffman, 1963; Paetzold, Dipboye, & Eslbach, 2008) and social dominance theory (Sidanius & Pratto, 1999), the purpose of this study was to examine the possibility of weight ...
E. Nicole Melton, George B. Cunningham
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Epistemic Uncertainty, Social Dominance Orientation, and Prejudices toward Women in Leadership Roles: Mediation and Moderation Analyses

open access: yesSocial Sciences
This research investigated the relation between the need for cognitive closure, social dominance orientation, and attitudes toward women as managers within a sample of Italian workers (N = 391) enrolled in a cross-sectional study.
Federico Contu   +2 more
doaj   +1 more source

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