Results 201 to 210 of about 449,708 (313)

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

AI, universal basic income, and power: symbolic violence in the tech elite's narrative. [PDF]

Front Artif Intell
Bélisle-Pipon JC.
europepmc   +1 more source

Bangladesh: Economic Growth in a Vulnerable Limited Access Order [PDF]

, 2013
Khan, Mushtaq
core   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Varieties of Economic Elites? Preliminary Results From the World Elite Database (WED). [PDF]

Br J Sociol
Bühlmann F, Christesen CA, Cousin B, Denord F, Ellersgaard CH, Lagneau-Ymonet P, Larsen AG, Savage M, Thine S, Young K, Araujo P, Arrigoni P, Atria J, Benz P, Behr J, Botelho MDC, Butt A, Casanova P, Clemente-Casinhas L, Castellani A, Cescon F, Dagnes J, Debska H, Delval AS, Dragun V, Egas A, Emilsson K, Fan X, Fu F, Gentile J, Gomes O, Gronwald V, Heredia M, Hjellbrekke J, Honório J, Huang J, Inkley J, Johansson H, Koiranen I, Koivula A, Kuusela H, Levita G, Ling C, Lu P, Lukas M, Lunding J, Mahmoudzadeh M, McQuade S, Méndez ML, Nunes N, O'Brien S, Otero G, Pagnini M, Pelfini A, Pereira J, Roa C, Rossier T, Saga ML, Santana D, Schneickert C, Schimpfössl E, Schoenberger F, Solipa I, Trembaczowski Ł, Toft M, Vale S, Vasconcelos P, Velazco JQ, Warczok T, Yu X.   +69 more
europepmc   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

"Who Islamises us?": Does political ideology moderate the effects of exposure to different Great Replacement Conspiracy explanations on radical collective action against different targets? [PDF]

Br J Soc Psychol
Çakmak H, Mang V, Long F.
europepmc   +1 more source

Vicarious Revolutionaries: Martial Discourse and the Origins of Mass Party Competition in the United States, 1789-1848 [PDF]

, 2010
Adams, Adams, Aldrich, Althusser, Ammon, Ashworth, Bailyn, Baker, Benson, Buchanan, Cedric de Leon, Clay, Clay, Clay, Cornell, Dahl, Dangerfield, Dunn, Duverger, Ferling, Formisano, Gienapp, Goodman, Grodzins, Hamilton, Hamilton, Hofstadter, Howe, Jackson, Jefferson, Jefferson, Jefferson, Jensen, Key, Keyssar, Kimeldorf, Larson, Lenner, Leonard, Lipset, Madison, McCormick, Monroe, Monroe, Moore, Nichols, O'Donnell, Paige, Patchell, Peeler, Robertson, Rokkan, Schattschneider, Schlesinger, Schlesinger, Schwartz, Sellers, Sharp, Shefter, Starr, Stephens, Therborn, Thompson, Thornton, Van Buren, Van Buren, Waldstreicher, Washington, Watson, Watts, Weber, Weisberger, Wiebe, Wilentz, Wilentz, Winn, Wood, Zeitlin   +77 more
core   +3 more sources

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source