Results 81 to 90 of about 45,860 (246)

Social Finance and Financing Social Enterprises: An Islamic Finance Prospective

European Journal of Islamic Finance, 2019
Enterprises that have a dual objective of generating positive social impact and financial economic benefit turned to be vital with the increased level of poverty and other major social problems accompanied with limited public spending.
Paolo Pietro Biancone, Maha Radwan
doaj   +1 more source

External Support for Elderly Care Social Enterprises in China: A Government-Society-Family Framework of Analysis. [PDF]

Int J Environ Res Public Health, 2022
Li H, Huang J, Liu J.
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

La fabrication contextuelle de l’hybridité en entreprise sociale : l’accompagnement socio‑professionnel en situation de travail

Activités
This article investigates socio-professional support practices in a social enterprise. Within such a “hybrid” system, the productive dimension of work is the means used to help adults with mental health problems to (re)develop social and professional ...
Ayla Bimonte
doaj   +1 more source

COVID-19 and the role of Voluntary, Community, and Social Enterprises in northern England in responding to the needs of marginalised communities: a qualitative focus group study. [PDF]

Lancet, 2022
Scott S, McGowan VJ, Wildman JM, Bidmead E, Hartley J, Mathews C, James B, Sullivan C, Bambra C, Sowden S.   +9 more
europepmc   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Policies and Instruments for Social Development

Journal of Innovations and Sustainability, 2018
Current paper presents a book review made by Prof. Dr. Margarita Bogdanova on the monograph “Policies and instruments for social development” – an edition of Innovations and Sustainability Academy – Bulgaria authored by Corresponding Member of the ...
Margarita Bogdanova
doaj  

Slowed Down Economisation: The Persistence of Alternative Trade Organisations

Swiss Journal of Sociology, 2018
Have Swiss Alternative Trade Organizations (ATOs) valorized economic aspects at the expense of their social mission for the longer term? From a historical perspective (1974–2013), this article shows how these social enterprises have maintained their ...
Arnold Nadine, Hammer Isabel
doaj   +1 more source