Results 141 to 150 of about 5,180,562 (321)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

How Can Overlooking Social Interactions, Space Familiarity or Other “Invisible Landscapes” Shaping Animal Movement Bias Habitat Selection Estimations and Species Distribution Predictions?

open access: yesEcology and Evolution
Species' future distributions are commonly predicted using models that link the likelihood of occurrence of individuals to the environment. Although animals' movements are influenced by physical and non‐physical landscapes, for example related to ...
Romain Dejeante   +2 more
doaj   +1 more source

Maternal behavior influences vocal practice and learning processes in the greater sac-winged bat

open access: yeseLife
Learning, particularly vocal learning, is often a social process. In human infants, it is well-established that social interactions influence speech acquisition and are hypothesized to modulate attentiveness and sensory processes, thereby affecting the ...
Ahana Aurora Fernandez   +3 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

PSYCHOLOGICAL DETERMINANTS OF THE SHAPING OF PROSOCIAL BEHAVIOR OF ADOLESCENTS IN MIXED REALITY

open access: yesRussian Journal of Education and Psychology
Background. The study of psychological determinants of shaping prosocial behavior of adolescents is connected with the need of society in the education of a prosperous personality with an active social position.
Svetlana V. Lantsova
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

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