Results 191 to 200 of about 14,038,368 (304)

Activity-friendly environments for active aging: The physical, social, and technology environments

Frontiers in Public Health, 2023
Erja Portegijs, Chanam Lee, Xuemei Zhu
doaj   +1 more source

From Childhood to Adulthood: A Mixed-Methods Exploration of Social Environments and Psychological Well-Being in Predominantly Black American Urban Communities. [PDF]

J Community Psychol
Mousavi-Raad A, Palimaru AI, Dastidar MG, Rosso AL, Dubowitz T, Hill-Jarrett TG, Gary-Webb TL, Pedersen SL, Troxel WM.   +8 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Ageing effects of social environments in 'non-social' insects. [PDF]

Philos Trans R Soc Lond B Biol Sci
Harrison LM, Churchill ER, Fairweather M, Fairweather M, Smithson CH, Chapman T, Bretman A.   +6 more
europepmc   +1 more source

Exploring links between personality traits and their social and non-social environments in wild poison frogs. [PDF]

Behav Ecol Sociobiol, 2022
Peignier M, Araya-Ajoy YG, Bégué L, Chaloupka S, Dellefont K, Leeb C, Walsh P, Ringler M, Ringler E.   +8 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Fast females, slow males: accelerated ageing and reproductive senescence in <i>Drosophila melanogaster</i> females across diverse social environments. [PDF]

Evol Lett
Harrison LM, Hughes J, Bretman A, Maklakov AA, Chapman T.   +4 more
europepmc   +1 more source

Multi-Dimensional Comparison of the Impact Mechanism of the Self-Rated Health Status of Urban and Rural Residents in Chinese Social Environments. [PDF]

Int J Environ Res Public Health, 2022
Yu C, Zhang X, Gao J.
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Resident and house manager perceptions of social environments in sober living houses: Associations with length of stay. [PDF]

J Community Psychol, 2021
Mahoney E, Witbrodt J, Mericle AA, Polcin DL.   +3 more
europepmc   +1 more source