Results 91 to 100 of about 13,563,483 (297)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Book review – Social Europe: From vision to vigour, Björn Hacker, Brussels, 2023, Publisher: Foundation for European Progressive Studies, ISBN: 978-3-8012-3105-7 [PDF]

open access: yesRomanian Journal of European Affairs
This book, authored by Björn Hacker, was published by the Foundation for European Progressive Studies (FEPS), within its Primer Series, in November 2023.
Klára Fóti
doaj  

Informing policy with health labour market analysis to improve availability of family doctors in Tajikistan

open access: yesHuman Resources for Health
Background Tajikistan has embarked on health reforms to orient the health system towards primary health care (PHC). The health labour market analysis (HLMA) was initiated by the Ministry of Health with the World Health Organization (WHO) on policy ...
Jamoliddin Abdullozoda   +12 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Responsible innovation in start-ups: entrepreneurial perspectives and formalisation of social responsibility

open access: yesJournal of Responsible Innovation
Start-ups are significant incubators of innovation. Notwithstanding, they have largely been ignored in the field of Responsible Innovation (RI). To address this shortcoming, the social responsibility for start-ups model (SRSM) for the embedment of RI in ...
Simeon Veloudis   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible poverty: migrants, new social policies and the risk of exclusion

open access: yes, 2006
This chapter deals with transformations of social policies in recent years and the ways they might have affected migrants, namely referred to a particular set of policies of assistance against the risk of poverty.
G. Procacci
core   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Referral pathways into the NHS Digital Weight Management Programme for musculoskeletal and perioperative patients: rapid process evaluation

open access: yesHealth and Social Care Delivery Research
Background The National Health Service in England is piloting an extension of access to its Digital Weight Management Programme, a digital service to support behavioural and lifestyle changes for weight loss.
Stephanie Stockwell   +5 more
doaj   +1 more source

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