Results 61 to 70 of about 13,492,077 (298)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Outpatient services and primary care: scoping review, substudies and international comparisons

open access: yesHealth Services and Delivery Research, 2016
Aim: This study updates a previous scoping review published by the National Institute for Health Research (NIHR) in 2006 (Roland M, McDonald R, Sibbald B.
Eleanor Winpenny   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

‘For a Social Europe’

open access: yes, 2022
Abstract This chapter examines the efforts undertaken by the then rising European Left—especially European socialist parties—to finally outline a concrete programme for a ‘social Europe’ in the run-up to the adoption of the European Community’s (EC’s) first Social Action Programme (1972–4).
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Social Europe, the Road not Taken

open access: yes, 2022
This book examines the European Left’s attempt to think and give shape to an alternative type of European integration—a ‘social Europe’—during the long 1970s. Based on fresh archival research, it shows that the western European Left—in particular, social
Andry, Aurélie Dianara
core   +1 more source

CHINESE-RUSSIAN PARTNERSHIP AND STRATEGIC COOPERATION

open access: yesСравнительная политика, 2019
For most of the time since the establishment of the Chinese-Russian strategic partnership, diplomatic interaction was the main area of strategic cooperation between the two parties.
Liu Fenghua
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Participation of Lithuanian Innovative SME’s in the European Union Single Market: Political and Legal Aspects [PDF]

open access: yesRevista de Management Comparat International, 2014
The aim: is to study political and legal aspects of Lithuanian SMEs performance in the EU single market. To achieve this aim three tasks were solved: to highlight the linkage between internationalisation and innovation as well as SMEs’ performance in the
Živilė PAUŽAITE, Jurgita BARYNIENE
doaj  

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