Results 51 to 60 of about 349,377 (212)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Outpatient services and primary care: scoping review, substudies and international comparisons
Health Services and Delivery Research, 2016 Aim: This study updates a previous scoping review published by the National Institute for Health Research (NIHR) in 2006 (Roland M, McDonald R, Sibbald B.
Eleanor Winpenny +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
CHINESE-RUSSIAN PARTNERSHIP AND STRATEGIC COOPERATION
Сравнительная политика, 2019 For most of the time since the establishment of the Chinese-Russian strategic partnership, diplomatic interaction was the main area of strategic cooperation between the two parties.
Liu Fenghua
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Participation of Lithuanian Innovative SME’s in the European Union Single Market: Political and Legal Aspects [PDF]
Revista de Management Comparat International, 2014 The aim: is to study political and legal aspects of Lithuanian SMEs performance in the EU single market. To achieve this aim three tasks were solved: to highlight the linkage between internationalisation and innovation as well as SMEs’ performance in the
Živilė PAUŽAITE, Jurgita BARYNIENE
doaj
Moments of the Negative. Two Small Nihilist Episodes from the 1940s [PDF]
PhainomenaEvoking Leo Strauss’s 1941 text “German Nihilism” and his forceful claim that nihilism is above all “the rejection of the principles of civilization as such,” my intention is to thematize the possible forms of coexistence that survive and develop despite
Petar Bojanić
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source