Results 51 to 60 of about 333,781 (261)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Outpatient services and primary care: scoping review, substudies and international comparisons

open access: yesHealth Services and Delivery Research, 2016
Aim: This study updates a previous scoping review published by the National Institute for Health Research (NIHR) in 2006 (Roland M, McDonald R, Sibbald B.
Eleanor Winpenny   +7 more
doaj   +1 more source

‘For a Social Europe’

open access: yes, 2022
Abstract This chapter examines the efforts undertaken by the then rising European Left—especially European socialist parties—to finally outline a concrete programme for a ‘social Europe’ in the run-up to the adoption of the European Community’s (EC’s) first Social Action Programme (1972–4).
openaire   +1 more source

Researching social Europe on the move

open access: yes, 2022
Developments occurring at the supranational level have prompted a lively scholarly debate about the nature and impact of "social Europe". This research trajectory includes the shift from early research focused extensively on formal social rights for mobile citizens, to the early 2000s, and a focus on the open method of coordination and its influence ...
Caroline De la Porte, Ilaria Madama
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Opinion of society as a basis of international relations — analysis of data of public-opinion polls «how citizens of China cognize the world?» [PDF]

open access: yesЭкономика региона, 2012
International links of China were intensified with the realization of policy of reforms. It becomes relevant to understand, how citizens of China cognize the world.
Pan Daly
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

CHINESE-RUSSIAN PARTNERSHIP AND STRATEGIC COOPERATION

open access: yesСравнительная политика, 2019
For most of the time since the establishment of the Chinese-Russian strategic partnership, diplomatic interaction was the main area of strategic cooperation between the two parties.
Liu Fenghua
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Home - About - Disclaimer - Privacy