Results 61 to 70 of about 44,092 (210)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Health and social inequality in Europe [PDF]
BMJ, 1994 In most European countries health has been shown to be linked to social circumstances--gradients in health status have persisted for decades, despite major changes in the principal causes of death. In central and eastern Europe life expectancy has stagnated since the mid-60s, whereas in the West it has increased; but even in the West it is related to ...
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Book review – Social Europe: From vision to vigour, Björn Hacker, Brussels, 2023, Publisher: Foundation for European Progressive Studies, ISBN: 978-3-8012-3105-7 [PDF]
Romanian Journal of European AffairsThis book, authored by Björn Hacker, was published by the Foundation for European Progressive Studies (FEPS), within its Primer Series, in November 2023.
Klára Fóti
doaj
Human Resources for HealthBackground Tajikistan has embarked on health reforms to orient the health system towards primary health care (PHC). The health labour market analysis (HLMA) was initiated by the Ministry of Health with the World Health Organization (WHO) on policy ...
Jamoliddin Abdullozoda +12 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Journal of Responsible InnovationStart-ups are significant incubators of innovation. Notwithstanding, they have largely been ignored in the field of Responsible Innovation (RI). To address this shortcoming, the social responsibility for start-ups model (SRSM) for the embedment of RI in ...
Simeon Veloudis +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
World Electric Vehicle JournalThis study aims to expand the current understanding of the antecedents and consequences of green purchase intention within the context of perceived green value (PGV). This study uniquely combines PLS-SEM and NCA to provide a comprehensive analysis of the
Haipeng Zhao +3 more
doaj +1 more source