Results 61 to 70 of about 333,781 (261)
Italian Labour Law e-JournalMore than one year after the deadline for the transposition of the European Minimum Wage Directive into national law, this contribution analyses the impact which the Directive already had on minimum wage setting and collective bargaining at national ...
Torsten Müller
doaj +1 more source
Participation of Lithuanian Innovative SME’s in the European Union Single Market: Political and Legal Aspects [PDF]
Revista de Management Comparat International, 2014 The aim: is to study political and legal aspects of Lithuanian SMEs performance in the EU single market. To achieve this aim three tasks were solved: to highlight the linkage between internationalisation and innovation as well as SMEs’ performance in the
Živilė PAUŽAITE, Jurgita BARYNIENE
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Moments of the Negative. Two Small Nihilist Episodes from the 1940s [PDF]
PhainomenaEvoking Leo Strauss’s 1941 text “German Nihilism” and his forceful claim that nihilism is above all “the rejection of the principles of civilization as such,” my intention is to thematize the possible forms of coexistence that survive and develop despite
Petar Bojanić
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Book review – Social Europe: From vision to vigour, Björn Hacker, Brussels, 2023, Publisher: Foundation for European Progressive Studies, ISBN: 978-3-8012-3105-7 [PDF]
Romanian Journal of European AffairsThis book, authored by Björn Hacker, was published by the Foundation for European Progressive Studies (FEPS), within its Primer Series, in November 2023.
Klára Fóti
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source