Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The co-evolution of the “social” and the “technology":a netnographic study of Social movements in virtual worlds [PDF]
, 2012 Virtual worlds provide new forms of social interaction. They offer alternative spaces where social functions can be carried out in online three-dimensional virtual environments.
Gardner, Lesley +2 more
core
The Price equation and the unity of social evolution theory. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2020 Lehtonen J.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Anonymous (and other) social experience and the evolution of cooperation by reciprocity
, 2010 Institut für Ökologie und Evolution ...
Taborsky, Michael
core
How Society Changes: Sociological Enlightenment and a Theory of Social Evolution for Freedom. [PDF]
Am Sociol, 2020 Tada M.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Scale and information-processing thresholds in Holocene social evolution. [PDF]
Nat Commun, 2020 Shin J +5 more
europepmc +1 more source
Form, function, and evolution of worker–worker social carrying in ants [PDF]
Arik Dorfman +2 more
openalex +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source