Results 71 to 80 of about 14,672,329 (357)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The molecular basis of socially induced egg-size plasticity in honey bees

eLife, 2022
Reproduction involves the investment of resources into offspring. Although variation in reproductive effort often affects the number of offspring, adjustments of propagule size are also found in numerous species, including the Western honey bee, Apis ...
Bin Han, Qiaohong Wei, Esmaeil Amiri, Han Hu, Lifeng Meng, Micheline K Strand, David R Tarpy, Shufa Xu, Jianke Li, Olav Rueppell   +9 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures

BMC Biology
Background Social behavior and social organization have major influences on individual health and fitness. Yet, biomedical research focuses on studying a few genotypes under impoverished social conditions.
Caleb C. Vogt, Matthew N. Zipple, Daniel D. Sprockett, Caitlin H. Miller, Summer X. Hardy, Matthew K. Arthur, Adam M. Greenstein, Melanie S. Colvin, Lucie M. Michel, Andrew H. Moeller, Michael J. Sheehan   +10 more
doaj   +1 more source

Kin discrimination, negative relatedness, and how to distinguish between selfishness and spite

Evolution Letters, 2020
Spiteful behaviors occur when an actor harms its own fitness to inflict harm on the fitness of others. Several papers have predicted that spite can be favored in sufficiently small populations, even when the harming behavior is directed indiscriminately ...
Matishalin Patel, Stuart A. West, Jay M. Biernaskie   +2 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Group formation and social evolution: a computational model

, 2008
The tendency to organise into groups is a fundamental property of human nature. Despite this, many models of social network evolution consider the emergence of community structure as a side effect of other processes, rather than as a mechanism driving ...
Bullock, Seth, Geard, Nicholas
core   +1 more source

Engineering Projects in Community Service (EPICS) in High Schools: Subtle but Potentially Important Student Gains Detected from Human-Centered Curriculum Design

Education Sciences, 2019
A major goal in Engineering training in the U.S. is to continue to both grow and diversify the field. Project- and service-based forms of experiential, problem-based learning are often implemented with this as a goal, and Engineering Projects in ...
Alissa Ruth, Joseph Hackman, Alexandra Brewis, Tameka Spence, Rachel Luchmun, Jennifer Velez, Tirupalavanam G. Ganesh   +6 more
doaj   +1 more source

Social Bacteriophages

Microorganisms, 2020
Despite their simplicity, viruses can display social-like interactions such as cooperation, communication, and cheating. Focusing on bacteriophages, here we review features including viral product sharing, cooperative evasion of antiviral defenses ...
Pilar Domingo-Calap, Lucas Mora-Quilis, Rafael Sanjuán   +2 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source