Results 221 to 230 of about 12,563,706 (287)

Children's Reasoning about Challenging Social Exclusion of Peers with Learning Difficulties. [PDF]

Int J Behav Dev
Barth C, Killen M, Grütter J.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The relationship between social exclusion and loneliness with balance, falls and, quality of life in community-dwelling elderly individuals. [PDF]

BMC Geriatr
Ergan M, Keskin T, Başkurt Z, Başkurt F.   +3 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Understanding social exclusion among midlife and older family caregivers of Individuals with age related cognitive declines: results from photo-based participatory study. [PDF]

BMC Geriatr
Urbaniak A, Szczerbińska K, Perek-Białas J.   +2 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The impact of social exclusion and interpersonal trust on aggressive behavior among left-behind middle school students. [PDF]

BMC Psychol
Yu J, Fan X, Liu W, Du Y.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Investigation of attachment social exclusion and risky behaviors in adolescents. [PDF]

BMC Psychol
Sezer F, Gürtepe A.
europepmc   +1 more source

Impact of social exclusion on salivary progesterone and estradiol in women with borderline personality disorder. [PDF]

Borderline Personal Disord Emot Dysregul
Barthauer M, Graumann L, Cho AB, Kulakova E, Deuter CE, Wolf OT, Hellmann-Regen J, Roepke S, Otte C, Wingenfeld K.   +9 more
europepmc   +1 more source