Results 131 to 140 of about 19,778,298 (257)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The Influence of Social Context on Language Style in Barbie (2023) Film

open access: yes
This research aims to investigate the types of language styles used in Barbie film and investigate more deeply social context contributions to the language style choice in Barbie film. The method of the research uses qualitative descriptive analysis. The
Tuty handayani, Fatimah Az Zahra
core   +1 more source

رابطه‌ی بین ارزش‌های فردی (ابزاری و نهایی) و حرفه‌ای در بین پرستاران بیمارستان‌های وابسته به دانشگاه علوم پزشکی اصفهان

open access: yesمدیریت اطلاعات سلامت, 2012
مقدمه: وجود هم‌گرایی بین ارزش‌ها در محیط‌های شغلی، نقشی تعیین کننده در ایجاد برون‌دادهای مثبت فردی و سازمانی ایفا می‌کند. از آنجایی که پرستاری حرفه‌ای است که در شرایط سخت بیماری، خدمات ارزشمندی را به جامعه ارایه می‌دهد، پژوهش حاضر با هدف شناسایی هم‌گرایی
Azadeh Askari   +2 more
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Prevalence of malnutrition in under 5-year old children in Birjand city in 2011

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2013
Background and Aim: Malnutrition of children, which has undesirable effects on mental and physical health of them, is one of the important health problems throughout the world particularly in developing countries.
azita fesharakinia   +1 more
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

What effect does fasting in Ramadan have on women\'s health? a review [PDF]

open access: yesPayesh
Objective(s): Ramadan intermittent fasting is a form of Sharia in which Muslims refrain from consuming food and drinks for thirty consecutive days from before sunrise to after sunset.
Fatemeh Hosseini, Reyhaneh Hassanshahi
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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