Results 91 to 100 of about 166,356 (331)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Economic boom and social mobility: The Irish experience [PDF]
, 2004 In this paper we examine the consequences for social mobility patterns of the unprecedented period of economic growth experienced in Ireland over the 1990s and the implications of developments for current theories of social fluidity.
Layte, Richard, Whelan, Christopher T.
core
Constructing dementia and dementia care: daily practices in a day care setting [PDF]
, 2005 • Summary:This article explores the ways in which dementia can be constructed and maintained by the actions, and received ideas concerning dementia, of social care staff practising in a local authority day care setting in the UK.The article is set ...
Parker, Jonathan
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ambulantage et services à la mobilité : les carrefours commerciaux à mexico
Cybergeo, 2007 Among various urban changes, the intensification of intra-urban mobility is characteristic of the contemporary phenomenon known as metropolization. In this context, we examine here the services brought to everyday urban travellers, through the study of ...
Jérôme Monnet +2 more
doaj +1 more source
, 2011 Social work has a long and significant history in the use of the 'self'. The first part of this paper is a contextualising discussion around recent reforms to social work.
Barnard, A
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Social Navigation and the Refugee Crisis: Traversing “Archipelagos” of Uncertainty
Media and Communication, 2019 This reflection considers the thematic issue “Refugee Crises Disclosed: Intersections between Media, Communication and Forced Migration Processes” through the lens of social navigation which takes into account the fluidity and uncertainty of the refugee ...
Melissa Wall
doaj +1 more source
Is 'gender-sensitive education' a useful concept for educational policy? [PDF]
, 2014 This article responds to Astrid Sinnes and Marianne Løken’s article ‘Gendered education in a gendered world: Looking beyond cosmetic solutions to the gender gap in science’ by exploring the idea of ‘gender-sensitive’ education and its usefulness in ...
Forde, Christine
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source