Results 121 to 130 of about 166,356 (331)

Escape to the beach : pre-retirement in-migrants' narratives of change, place and identity : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Sociology at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
The pre-retirement cohort (45-65 years) that migrates within Aotearoa New Zealand remains largely ignored in social research. This cohort encompasses people experiencing an emergent mid-life life-stage characterized by increased fluidity between ...
Pennell, Stella Maria
core  

Network [PDF]

open access: yes, 2006
Network is a device for organising and conceptualising non-linear complexity. Networks defy narrative, chronology and thus also genealogy because they entail a multiplicity of traces.
Loon, J van
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Empowering the Democratic Resistance in Syria [PDF]

open access: yes, 2013
When the peaceful uprising in Syria started in spring 2011 turned into an armed resistance after a few months in the face of savage repression by the Assad regime. Since then, the activists who picked up arms became dependent on support in money and arms
Felix Legrand
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

L’invention des routines

open access: yesEspace populations sociétés, 2015
Speaking of routines, in social sciences easily carries connotations related to alienation. Routines, it is said, come from the fact that individuals and households, depend on heavy macro-social time constraints that impose their mechanical time on their
Frédéric de Coninck
doaj   +1 more source

Book review: networks of outrage and hope: social movements in the internet age by Manuel Castells [PDF]

open access: yes, 2016
In the second edition of Networks of Outrage and Hope: Social Movements in the Internet Age, sociologist Manuel Castells conceptualises the relationship between social movements and the internet age through the notion of ‘the networked social movement ...
Levy, Helton
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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