A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Lifespan Fluidity and Its Biological Limitations in Socio-Economic Health Differences. [PDF]
Finch CE, Jylhä MK.
europepmc +1 more source
Explaining the Irish Pattern of Social Fluidity: The Role ofthe Political. ESRI Working Paper No. 25, June 1991 [PDF]
Richard Breen, Christopher T. Whelan
openalex
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Proprioception and Cognitive Polarization in Autism: The Bipolar Tensile Model. [PDF]
Sanna M.
europepmc +1 more source
Decision letter: Social fluidity mobilizes contagion in human and animal populations
Jari Saramäki, Niel Hens
openalex +1 more source
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
Queer-religious symbol analysis (QRSA): A semiotic method for reframing Hindu iconography. [PDF]
Ac PS, Gk C.
europepmc +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Enhancing sperm resilience: protective effects of ectoine on post-thaw bovine sperm quality under environmental stress conditions. [PDF]
Weldon K, Fair S.
europepmc +1 more source

