Results 121 to 130 of about 4,443,624 (310)
Systematic Review: Comparative Efficacy of the Picture Exchange Communication System (PECS) to Other Augmentative Communication Systems in Increasing Social Communication Skills in Children with Autism Spectrum Disorder [PDF]
, 2018 Purpose: This systematic review aims to compare the efficacy of the Picture Exchange Communication System (PECS) to other forms of Augmentative and Alternative Communication (AAC) in increasing social communication skills in children with Autism Spectrum
Johnson, Alyssa +3 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In Italy, social capital can bridge disconnected communities and encourage innovation [PDF]
, 2012 Economic performance is highly dependent upon underlying social and institutional structures. Riccardo Crescenzi and Luisa Gagliardi write that Italy has proven a very interesting ‘laboratory’ to test this link by looking at the impact of different forms
Crescenzi, Riccardo, Gagliardi, Luisa
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Performative Social Science and Psychology
Forum: Qualitative Social Research, 2010 This article presents an overview of "Performative Social Science," which is defined as the deployment of different forms of artistic performance in the execution of a scientific project.
Mary Gergen, Kenneth J. Gergen
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
India's Socially Regulated Economy [PDF]
By far the larger part of the contemporary Indian economy - judged by measures as disparate as GDP and livelihoods - is not directly regulated by the state. It is regulated through social institutions.
Barbara Harriss-White (QEH)
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source