Results 131 to 140 of about 4,443,624 (310)

Terrorism as form of social entrepreneurship

open access: yesDIEM : Dubrovnik International Economic Meeting, 2017
Terrorism is linked with some form of social entrepreneurship. In order to ensure the survival of terrorist organisations, terrorist must acquire entrepreneurial and managerial skills and take over some business strategies. The view of terrorists as entrepreneurs is not new.
Krželj-Čolović, Zorica   +1 more
openaire   +4 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

SOME COMMENTS ON EDUCATION FOR ENTREPRENEURSHIP [PDF]

open access: yes
Author stresses the increasing role of education for entrepreneurship within the formal system of education, as well as the importance of individual’s socialization.
Prof. Marijan Cingula Ph. D
core  

The New Generation of Community Foundations [PDF]

open access: yes, 2012
Community foundations have enjoyed considerable growth in recent years, not only in their number but also in their character. This emergence of a "new generation" of community foundations is occurring within a larger context of other emerging forms of ...
Alison Mathie   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The social construction of competences and the forms of transitions in industrial territories [PDF]

open access: yes
The purpose of this communication is to present some reflexions on the transformation and the evolution of three industrial regions located in three Mediterranean countries (France, Spain and Italy).
Ariel Mendez, Roberto Herranz
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

IS SOCIAL CAPITAL REALLY CAPITAL? [PDF]

open access: yes
Social capital in the past two decades has emerged as a dominant paradigm in the various social science disciplines. However, its adoption by the different social science disciplines has led to multiple and often conflicting definitions of social capital.
Robison, Lindon J.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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